Bookmakers make Carlisle United odds-on favourites to see off FA Cup heroes Grimsby Town today.

Whilst the Mariners this week claimed a stunning away win against Premier League side Southampton in the cup's fifth round, they are predicted to come off second-best at Brunton Park in their return to League Two action.

High-flying United are as short as 3/4 with SkyBet to claim a third straight win, with other prices of 4/5 (Bet365) and 17/20 (Betfair) on offer.

Seven of Grimsby's ten league wins have come on the road this season, with the 16th-placed Mariners better travellers than home performers.

They are 15/4 with vbet to win at Brunton Park, and 7/2 with Coral.

The draw is 13/5.

Despite being a substitute for third-placed Carlisle's last two games, Kristian Dennis is favourite to get the opening goal this afternoon against a visiting side who will include former Blues keeper Max Crocombe.

United's top scorer is priced 9/2 to find the net first against his former club.

Omari Patrick and Joe Garner, who have started in attack against Colchester United and Crawley Town, are both 6/1 along with John-Kymani Gordon.

Owen Moxon, who hit the opener when the clubs met at Blundell Park earlier in the campaign, is 10/1 to score first today and claim his first Brunton Park goal in the process.

A second opening goal on successive weekends for Joel Senior, meanwhile, is 28/1.

Grimsby's midweek cup penalty hero Gavan Holohan is 18/1 to open the scoring against Paul Simpson's side, with others including Ryan Taylor at 10/1, John McAtee 10/1, Harry Clifton 14/1 and former Barrow man Anthony Driscoll-Glennon 50/1.

Carlisle are 8/1 for a second 2-1 win of the season against Paul Hurst's Mariners.

Grimsby are 16/1 to win by the same scoreline.

A goalless draw is 81/10...while a second consecutive 5/2 win for Simmo's side is 250/1.

Source: Oddschecker.